probiotics

 

 

 

What Are Probiotics?

Peter Cartwright investigates whether probiotics have any benefit, or whether they are just another health fad. 

Probiotics are appearing in increasing numbers. In the supermarket there are little bottles of milk drinks containing ‘friendly bacteria’, and there is a growing range of bio-yoghurts and similar fermented products. Health food stores and vitamin/mineral suppliers stock capsules and powders with names such as ‘acidophilus’.

But what exactly is a probiotic?

Probiotics are products containing special types of microbes (live microscopic creatures) which help to create a better mixture among the bacteria living in the human intestine. Each of us has billions upon billions of bacteria living in the lower gut. These resident bacteria are commonly known as the microflora, and some of these bacteria are more desirable than others. By consuming probiotics, the idea is to increase the numbers of the better bacteria.

We gain our microflora in the first few days of birth, and the mixture becomes fully developed from the time of weaning. One of the benefits of the microflora is that they prevent harmful microbes (pathogenic bacteria, viruses, fungi and parasites) from growing in the intestine and causing disease.

But the protective process sometimes called “competitive exclusion” does not always work. If you eat food that is seriously contaminated by harmful microbes, they may be so great in number that they become established despite the opposition of the microflora, leading to infectious diarrhoea.

Sometimes, antibiotics are prescribed to counter an infection, but in addition to attacking harmful bacteria, the antibiotics also kill the protective bacteria. The resulting “vacuum” in the lower intestines can make it easier for other harmful microbes to get established, leading to what is known as “antibiotic-associated diarrhoea”.

Certain long-term conditions have altered mixtures of bacteria in the microflora. People with Crohn’s disease and ulcerative colitis (UC) have a different mixture from people without these illnesses. There are more of the types that can be harmful and fewer of the beneficial types (e.g., lactobacilli and bifidobacteria).

Is there any evidence that taking probiotics can lead to improvements in health?

Over the last 10 years there has been a growing amount of scientific evidence that shows that probiotics can:

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reduce the likelihood of infectious diarrhoea developing

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reduce the time taken to recover from infectious diarrhoea

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work against antibiotic-associated diarrhoea

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reduce the severity of Crohn’s and UC.

If you have Crohn’s disease and an ileostomy or a colostomy, probiotics may be able to reduce the severity of your continuing inflammation.

There is a problem with probiotics, however. They cannot be prescribed by doctors as there are not classified as drugs.

Instead, they are food or food supplements. While this means that they can be purchased over the counter, it also means that the products are not allowed to claim that they treat or prevent disease.

It can therefore be difficult to know how to choose a probiotic that is likely to be effective in altering the microflora mixture and leading to better health.

Factors you should look for in a good product include:

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a large number of live beneficial bacteria

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survival through the stomach acid

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containing food to enable the bacteria to live and grow as they travel through the intestine

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types of bacteria that can attach to the gut wall and so stay longer in the intestine

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research evidence of health benefits

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a mixture of bacterial species so that there is a broader range of effect.

Some of the information is on product packaging, and some can be found on company websites.

Despite the difficulties in identifying good quality probiotics, it is reassuring to know that probiotics have a very good safety profile, with almost no side effects reported. The new knowledge about probiotics offers hope of improved digestive health by working with the gut microflora rather than against them.

First appeared in Converse®, issue 3, September 2003. Kindly reproduced with permission of ConvaTec Ltd.
 

Copyright © Prentice Publishing 2003. All Rights Reserved.